Microsoft have released the Skype for Business 2015 Protocol Workloads Poster.
This can be obtained from :
One of the big changes that Microsoft alerted me on was the use of 443 to the edge from the Front End. Historically this was done via 4443.
Another thing that has just gained my attention is the use of H264AVC rather than SVC from the VIS server. This means that it should allow for use outside of traditional Video Conferencing Endpoints.